Our team with the guidance of Prof. Vangelis and Prof. Zyda are trying to help CHLA create innovative therapies and clinical research for cystic fibrosis. Our aim is to create fun VR games based on the three breathing phases, i.e. inhalation, pause, and exhalation. Our main focus has been to make the game self-explanatory and provide intuitive feedback to the users. Our second concern has been to keep the kids engaged in the games using a good balance of challenge or efforts, encouragement and visual effects.